STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pksGhydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)    
Predicted Functional Partners:
mvaA
hydroxymethylglutaryl-CoA reductase, degradative; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family.
 
 0.990
APE76949.1
Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.920
mvk
Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.842
APE76950.1
Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.841
pdhC
Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.806
fni
Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.794
acpP_1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.566
acpP_2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.566
dltC
D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
  
 
 0.566
APE76088.1
2-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.503
Your Current Organism:
Leuconostoc mesenteroides
NCBI taxonomy Id: 1245
Other names: ATCC 8293, Ascococcus mesenteroides, Betacoccus arabinosaceus, CCUG 30066, CIP 102305, DSM 20343, HAMBI 2347, JCM 6124, L. mesenteroides, LMG 6893, LMG:6893, Leuconostoc sp. 13HN, NBRC 100496, NCDO 523, NCTC 12954, NRRL B-3470, strain 12954
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