node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE76214.1 | dut | ARA02_02200 | ARA02_00710 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.940 |
APE76214.1 | tdk | ARA02_02200 | ARA02_07930 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
APE76214.1 | thyA_1 | ARA02_02200 | ARA02_02195 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.962 |
APE76214.1 | tmk | ARA02_02200 | ARA02_01300 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
APE76739.1 | tdk | ARA02_05115 | ARA02_07930 | Nucleoside 2-deoxyribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
bsr | tdk | ARA02_05675 | ARA02_07930 | Diadenosine tetraphosphate hydrolase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
cdd | tdk | ARA02_02120 | ARA02_07930 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
dut | APE76214.1 | ARA02_00710 | ARA02_02200 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
dut | tdk | ARA02_00710 | ARA02_07930 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
dut | thyA_1 | ARA02_00710 | ARA02_02195 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.964 |
dut | tmk | ARA02_00710 | ARA02_01300 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.947 |
efp | tdk | ARA02_07450 | ARA02_07930 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |
purD | pyrG | ARA02_03375 | ARA02_02490 | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.417 |
purD | tdk | ARA02_03375 | ARA02_07930 | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.494 |
pyrG | purD | ARA02_02490 | ARA02_03375 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. | 0.417 |
pyrG | tdk | ARA02_02490 | ARA02_07930 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
pyrG | thyA_1 | ARA02_02490 | ARA02_02195 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.429 |
tdk | APE76214.1 | ARA02_07930 | ARA02_02200 | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
tdk | APE76739.1 | ARA02_07930 | ARA02_05115 | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside 2-deoxyribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
tdk | bsr | ARA02_07930 | ARA02_05675 | Peptide chain release factor 1; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diadenosine tetraphosphate hydrolase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |