Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (159 aa)    
Predicted Functional Partners:
ribA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the DHBP synthase family.
 
 
 0.999
ANY10926.1
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 
 0.999
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.929
ANY11582.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
ribF
Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family.
     
 0.879
folP
Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.842
folE
GTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.808
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.804
rsmB
16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.707
Your Current Organism:
Leuconostoc lactis
NCBI taxonomy Id: 1246
Other names: ATCC 19256, CCUG 30064, CCUG 38887 [[Leuconostoc argentinum]], CIP 102422, CIP 103889 [[Leuconostoc argentinum]], DSM 20202, DSM 8581 [[Leuconostoc argentinum]], HAMBI 2346, JCM 11052 [[Leuconostoc argentinum]], JCM 6123, KCTC 3528, KCTC 3773 [[Leuconostoc argentinum]], L. lactis, LMG 8894, LMG:8894, Leuconostoc argentinum, Leuconostoc sp. LMG 22650, Leuconostoc sp. R-21065, NCFB 533, NCIMB 13091, NRRL B-3468, strain Gibson L5, strain L5, strain LL76 [[Leuconostoc argentinum]]
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