| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANY10928.1 | ANY10929.1 | BCR17_00235 | BCR17_00240 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.678 |
| ANY10928.1 | kup | BCR17_00235 | BCR17_00245 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Potassium transporter Kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.431 |
| ANY10929.1 | ANY10928.1 | BCR17_00240 | BCR17_00235 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.678 |
| ANY10929.1 | ANY11296.1 | BCR17_00240 | BCR17_02230 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.451 |
| ANY10929.1 | ANY11912.1 | BCR17_00240 | BCR17_05810 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| ANY10929.1 | dltA | BCR17_00240 | BCR17_06425 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.900 |
| ANY10929.1 | dltB | BCR17_00240 | BCR17_06430 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.900 |
| ANY10929.1 | dltC | BCR17_00240 | BCR17_06435 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.900 |
| ANY10929.1 | dltD | BCR17_00240 | BCR17_06440 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanyl-lipoteichoic acid biosynthesis protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| ANY10929.1 | kup | BCR17_00240 | BCR17_00245 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Potassium transporter Kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.483 |
| ANY10929.1 | sepF | BCR17_00240 | BCR17_01470 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.511 |
| ANY11296.1 | ANY10929.1 | BCR17_02230 | BCR17_00240 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.451 |
| ANY11912.1 | ANY10929.1 | BCR17_05810 | BCR17_00240 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| dltA | ANY10929.1 | BCR17_06425 | BCR17_00240 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| dltA | dltB | BCR17_06425 | BCR17_06430 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.999 |
| dltA | dltC | BCR17_06425 | BCR17_06435 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.999 |
| dltA | dltD | BCR17_06425 | BCR17_06440 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | D-alanyl-lipoteichoic acid biosynthesis protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| dltB | ANY10929.1 | BCR17_06430 | BCR17_00240 | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| dltB | dltA | BCR17_06430 | BCR17_06425 | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.999 |
| dltB | dltC | BCR17_06430 | BCR17_06435 | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.999 |