Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ccaCCA tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (401 aa)    
Predicted Functional Partners:
ANY12100.1
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
    0.872
ANY11015.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.835
ANY11014.1
Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.820
ANY11017.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.711
ANY12447.1
biotin--[acetyl-CoA-carboxylase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.696
ANY11927.1
biotin--[acetyl-CoA-carboxylase] ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.696
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
      0.687
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.623
rps1
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
 
    0.578
asnS
asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.574
Your Current Organism:
Leuconostoc lactis
NCBI taxonomy Id: 1246
Other names: ATCC 19256, CCUG 30064, CCUG 38887 [[Leuconostoc argentinum]], CIP 102422, CIP 103889 [[Leuconostoc argentinum]], DSM 20202, DSM 8581 [[Leuconostoc argentinum]], HAMBI 2346, JCM 11052 [[Leuconostoc argentinum]], JCM 6123, KCTC 3528, KCTC 3773 [[Leuconostoc argentinum]], L. lactis, LMG 8894, LMG:8894, Leuconostoc argentinum, Leuconostoc sp. LMG 22650, Leuconostoc sp. R-21065, NCFB 533, NCIMB 13091, NRRL B-3468, strain Gibson L5, strain L5, strain LL76 [[Leuconostoc argentinum]]
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