Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANY11075.1Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology. (800 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.772
divIB
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
   
 
 0.735
ANY11409.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family.
  
  
 0.691
ANY11205.1
Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
 
  
 0.637
ribA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.634
ANY10967.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.630
ANY12464.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.630
ANY12312.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.630
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.624
pknB
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.622
Your Current Organism:
Leuconostoc lactis
NCBI taxonomy Id: 1246
Other names: ATCC 19256, CCUG 30064, CCUG 38887 [[Leuconostoc argentinum]], CIP 102422, CIP 103889 [[Leuconostoc argentinum]], DSM 20202, DSM 8581 [[Leuconostoc argentinum]], HAMBI 2346, JCM 11052 [[Leuconostoc argentinum]], JCM 6123, KCTC 3528, KCTC 3773 [[Leuconostoc argentinum]], L. lactis, LMG 8894, LMG:8894, Leuconostoc argentinum, Leuconostoc sp. LMG 22650, Leuconostoc sp. R-21065, NCFB 533, NCIMB 13091, NRRL B-3468, strain Gibson L5, strain L5, strain LL76 [[Leuconostoc argentinum]]
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