PSACC_03696 protein (Paramicrosporidium saccamoebae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PSACC_03696

Fcf2 domain-containing protein. (158 aa)

Predicted Functional Partners:

PSACC_01017

0.992

PSACC_02391

0.991

PSACC_03049

0.990

PSACC_00481

0.986

PSACC_02930

0.981

PSACC_02762

0.981

PSACC_00937

0.981

PSACC_03490

0.979

PSACC_00172

0.979

PSACC_03362

0.978

Your Current Organism:

Paramicrosporidium saccamoebae

NCBI taxonomy Id: 1246581
Other names: KSL3, P. saccamoebae, Paramicrosporidium saccamoebae Corsaro et al., 2014, fungal sp. KSL3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PSACC_00172	PSACC_00481	A0A2H9TQK3	A0A2H9TPP3	Utp12 domain-containing protein.	Sas10 domain-containing protein.	0.992
PSACC_00172	PSACC_00937	A0A2H9TQK3	A0A2H9TNC9	Utp12 domain-containing protein.	U3 small nucleolar ribonucleoprotein MPP10.	0.999
PSACC_00172	PSACC_01017	A0A2H9TQK3	A0A2H9TN63	Utp12 domain-containing protein.	TRAUB-domain-containing protein.	0.996
PSACC_00172	PSACC_02391	A0A2H9TQK3	A0A2H9TJ49	Utp12 domain-containing protein.	Bms1-type G domain-containing protein.	0.998
PSACC_00172	PSACC_02762	A0A2H9TQK3	A0A2H9TI78	Utp12 domain-containing protein.	PINc domain-containing protein.	0.982
PSACC_00172	PSACC_02930	A0A2H9TQK3	A0A2H9THQ4	Utp12 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PSACC_00172	PSACC_03049	A0A2H9TQK3	A0A2H9THD4	Utp12 domain-containing protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.984
PSACC_00172	PSACC_03362	A0A2H9TQK3	A0A2H9TGC7	Utp12 domain-containing protein.	Utp6p.	0.997
PSACC_00172	PSACC_03490	A0A2H9TQK3	A0A2H9TG10	Utp12 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.998
PSACC_00172	PSACC_03696	A0A2H9TQK3	A0A2H9TFP1	Utp12 domain-containing protein.	Fcf2 domain-containing protein.	0.979
PSACC_00481	PSACC_00172	A0A2H9TPP3	A0A2H9TQK3	Sas10 domain-containing protein.	Utp12 domain-containing protein.	0.992
PSACC_00481	PSACC_00937	A0A2H9TPP3	A0A2H9TNC9	Sas10 domain-containing protein.	U3 small nucleolar ribonucleoprotein MPP10.	0.997
PSACC_00481	PSACC_01017	A0A2H9TPP3	A0A2H9TN63	Sas10 domain-containing protein.	TRAUB-domain-containing protein.	0.993
PSACC_00481	PSACC_02391	A0A2H9TPP3	A0A2H9TJ49	Sas10 domain-containing protein.	Bms1-type G domain-containing protein.	0.998
PSACC_00481	PSACC_02762	A0A2H9TPP3	A0A2H9TI78	Sas10 domain-containing protein.	PINc domain-containing protein.	0.999
PSACC_00481	PSACC_02930	A0A2H9TPP3	A0A2H9THQ4	Sas10 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.998
PSACC_00481	PSACC_03049	A0A2H9TPP3	A0A2H9THD4	Sas10 domain-containing protein.	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.	0.999
PSACC_00481	PSACC_03362	A0A2H9TPP3	A0A2H9TGC7	Sas10 domain-containing protein.	Utp6p.	0.998
PSACC_00481	PSACC_03490	A0A2H9TPP3	A0A2H9TG10	Sas10 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
PSACC_00481	PSACC_03696	A0A2H9TPP3	A0A2H9TFP1	Sas10 domain-containing protein.	Fcf2 domain-containing protein.	0.986

page 1 of 6

Network Stats

number of nodes:

6

number of edges:

9

average node degree:

3

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.0777

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006635

Fatty acid beta-oxidation

3 of 10

2.17

1.46

0.0017

GO:0006631

Fatty acid metabolic process

4 of 42

1.68

1.3

0.0017

GO:0006629

Lipid metabolic process

5 of 172

1.16

0.94

0.0018

GO:0006412

Translation

4 of 105

1.28

0.92

0.0048

GO:0044238

Primary metabolic process

10 of 1831

0.43

0.33

0.0097

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

4 of 55

1.56

1.17

0.0026

GO:0070403

NAD+ binding

2 of 3

2.52

1.14

0.0084

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

4 of 61

1.51

1.34

0.00069

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3915

Lipid oxidation, and 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

4 of 13

2.19

2.34

2.54e-05

CL:2855

Ribosome

4 of 33

1.78

0.00014

CL:4722

Oxidoreductase FAD-binding domain, and Response to nitrosative stress

2 of 6

2.22

1.15

0.0070

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rsi00360

Phenylalanine metabolism

5 of 15

2.22

3.73

1.96e-08

rsi00650

Butanoate metabolism

3 of 20

1.87

1.7

0.00030

rsi00362

Benzoate degradation

3 of 22

1.83

1.67

0.00031

rsi03010

Ribosome

4 of 54

1.57

1.61

0.00013

rsi00903

Limonene and pinene degradation

2 of 4

2.4

1.61

0.0010

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0036125

Fatty acid beta-oxidation multienzyme complex

3 of 6

2.4

2.02

0.00016

GOCC:0005840

Ribosome

4 of 37

1.73

1.72

0.00016

GOCC:0062077

phenylacetyl-CoA 1,2-epoxidase complex

2 of 3

2.52

1.34

0.0034

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

2.15

1.11

0.0082

GOCC:0032991

Protein-containing complex

7 of 574

0.78

0.59

0.0034

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

4 of 64

1.49

1.22

0.0014

KW-0001

2Fe-2S

2 of 8

2.1

1.04

0.0111

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF16113

Enoyl-CoA hydratase/isomerase

3 of 8

2.27

1.67

0.00069

PF02737

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain

2 of 3

2.52

1.04

0.0129

PF00970

Oxidoreductase FAD-binding domain

2 of 3

2.52

1.04

0.0129

PF00725

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

2 of 3

2.52

1.04

0.0129

PF00175

Oxidoreductase NAD-binding domain

2 of 3

2.52

1.04

0.0129

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About