STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFR_07965COG1253 Hemolysins and related proteins containing CBS domains. (455 aa)    
Predicted Functional Partners:
ybeY
Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.944
AFR_07970
Hypothetical protein.
  
    0.923
AFR_07955
COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.
  
  
 0.832
AFR_07945
Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
       0.606
AFR_29945
Putative rRNA methyltransferase; COG1189 Predicted rRNA methylase.
     
 0.560
AFR_07950
COG1680 Beta-lactamase class C and other penicillin binding proteins.
 
     0.518
era
GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.457
truA
Putative tRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
     0.438
Your Current Organism:
Actinoplanes friuliensis
NCBI taxonomy Id: 1246995
Other names: A. friuliensis DSM 7358, Actinoplanes friuliensis DSM 7358, Actinoplanes friuliensis HAG 010964
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.