STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFR_31170COG1397 ADP-ribosylglycohydrolase. (319 aa)    
Predicted Functional Partners:
AFR_42245
COG4295 Uncharacterized protein conserved in bacteria.
 
   
 0.639
thrS
COG0441 Threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.609
AFR_31175
Putative two-component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.560
AFR_36420
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
   
 
 0.507
AFR_31180
Putative two-component system sensor kinase; COG0642 Signal transduction histidine kinase.
 
     0.499
kptA
Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
   
 0.469
AFR_35195
COG4034 Uncharacterized protein conserved in archaea.
  
     0.453
AFR_32270
Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.
 
   
 0.416
AFR_00655
COG1397 ADP-ribosylglycohydrolase.
  
     0.405
Your Current Organism:
Actinoplanes friuliensis
NCBI taxonomy Id: 1246995
Other names: A. friuliensis DSM 7358, Actinoplanes friuliensis DSM 7358, Actinoplanes friuliensis HAG 010964
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