node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rplC | rplD | BN2475_90225 | BN2475_90224 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 0.999 |
rplC | rplM | BN2475_90225 | BN2475_470088 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rplC | rplS | BN2475_90225 | BN2475_250031 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.999 |
rplC | rplT | BN2475_90225 | BN2475_160016 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.999 |
rplC | rpmA | BN2475_90225 | BN2475_470180 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family. | 0.999 |
rplC | rpsB | BN2475_90225 | BN2475_120123 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal subunit protein S2; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
rplC | rpsG | BN2475_90225 | BN2475_500002 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal subunit protein S7, initiates assembly; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
rplC | rpsO | BN2475_90225 | BN2475_270186 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.999 |
rplC | rpsR | BN2475_90225 | BN2475_600109 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.999 |
rplC | smpB | BN2475_90225 | BN2475_120101 | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Trans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.997 |
rplD | rplC | BN2475_90224 | BN2475_90225 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
rplD | rplM | BN2475_90224 | BN2475_470088 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rplD | rplS | BN2475_90224 | BN2475_250031 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.999 |
rplD | rplT | BN2475_90224 | BN2475_160016 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.999 |
rplD | rpmA | BN2475_90224 | BN2475_470180 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family. | 0.999 |
rplD | rpsB | BN2475_90224 | BN2475_120123 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 30S ribosomal subunit protein S2; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
rplD | rpsG | BN2475_90224 | BN2475_500002 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 30S ribosomal subunit protein S7, initiates assembly; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
rplD | rpsO | BN2475_90224 | BN2475_270186 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.999 |
rplD | rpsR | BN2475_90224 | BN2475_600109 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.999 |
rplD | smpB | BN2475_90224 | BN2475_120101 | 50S ribosomal subunit protein L4, regulates expression of S10 operon; Forms part of the polypeptide exit tunnel. | Trans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.997 |