node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIT42559.1 | SIT44350.1 | BN2475_370092 | BN2475_470125 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.560 |
SIT42559.1 | SIT46977.1 | BN2475_370092 | BN2475_700088 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Heat shock protein DnaJ domain protein. | 0.749 |
SIT42559.1 | dnaJ | BN2475_370092 | BN2475_380039 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.749 |
SIT44349.1 | SIT44350.1 | BN2475_470124 | BN2475_470125 | Putative glyoxalase/bleomycin resistance protein, Dioxygenase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.736 |
SIT44350.1 | SIT42559.1 | BN2475_470125 | BN2475_370092 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.560 |
SIT44350.1 | SIT44349.1 | BN2475_470125 | BN2475_470124 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Putative glyoxalase/bleomycin resistance protein, Dioxygenase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.736 |
SIT44350.1 | SIT46977.1 | BN2475_470125 | BN2475_700088 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Heat shock protein DnaJ domain protein. | 0.561 |
SIT44350.1 | der | BN2475_470125 | BN2475_120218 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | GTPase involved in ribosome synthesis and maintenance; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.582 |
SIT44350.1 | dnaJ | BN2475_470125 | BN2475_380039 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...] | 0.568 |
SIT44350.1 | gidB | BN2475_470125 | BN2475_340129 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Methyltransferase, SAM-dependent methyltransferase, glucose-inhibited cell-division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.696 |
SIT44350.1 | mraW | BN2475_470125 | BN2475_470214 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | S-adenosyl-dependent methyltransferase activity on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.558 |
SIT44350.1 | prmA | BN2475_470125 | BN2475_470159 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Methylase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.889 |
SIT44350.1 | rlmB | BN2475_470125 | BN2475_130083 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 23S rRNA (Gm2251)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.579 |
SIT44350.1 | trmD | BN2475_470125 | BN2475_250032 | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.541 |
SIT46977.1 | SIT42559.1 | BN2475_700088 | BN2475_370092 | Heat shock protein DnaJ domain protein. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.749 |
SIT46977.1 | SIT44350.1 | BN2475_700088 | BN2475_470125 | Heat shock protein DnaJ domain protein. | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.561 |
SIT46977.1 | prmA | BN2475_700088 | BN2475_470159 | Heat shock protein DnaJ domain protein. | Methylase for 50S ribosomal subunit protein L11; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.822 |
SIT46977.1 | rlmB | BN2475_700088 | BN2475_130083 | Heat shock protein DnaJ domain protein. | 23S rRNA (Gm2251)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.926 |
der | SIT44350.1 | BN2475_120218 | BN2475_470125 | GTPase involved in ribosome synthesis and maintenance; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.582 |
der | gidB | BN2475_120218 | BN2475_340129 | GTPase involved in ribosome synthesis and maintenance; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Methyltransferase, SAM-dependent methyltransferase, glucose-inhibited cell-division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.698 |