STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maiA-4Putative maleylacetoacetate isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (214 aa)    
Predicted Functional Partners:
sspA
Stringent starvation protein A, regulator of transcription; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 
0.934
rpoC
RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.928
hmgA
Homogentisate 1,2-dioxygenase.
 
 
 0.921
hmgA-2
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.918
rpoA
RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.899
SIT42799.1
Fumarylacetoacetase.
 
 
 0.888
SIT37113.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase.
 
 
 0.866
SIT40581.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 
 0.862
nagK
Fumarylpyruvate hydrolase.
  
 
 0.843
hpd
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.809
Your Current Organism:
Paraburkholderia ribeironis
NCBI taxonomy Id: 1247936
Other names: Burkholderia sp. STM 7168, Burkholderia sp. STM 7217, Burkholderia sp. STM 7296, DSM 101188, LMG 29351, LMG:29351, P. ribeironis, Paraburkholderia ribeironis Bournaud et al. 2017, STM 7296, STM:7296
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