STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmDRNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (486 aa)    
Predicted Functional Partners:
D779_0600
Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
    0.824
tmcA
PutativeP-loop ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
  
    0.774
D779_0602
Hypothetical protein.
       0.736
D779_0603
Hypothetical protein.
       0.728
rlmB
23S rRNA (guanosine-2'-O-) -methyltransferase rlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
 
  
 0.681
trmB
tRNA (guanine46-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.675
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.623
D779_1365
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.606
dusA
tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
 
  
 0.597
rlmL
23S rRNA (guanine-N-2-) -methyltransferase rlmL; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
  
 0.588
Your Current Organism:
Imhoffiella purpurea
NCBI taxonomy Id: 1249627
Other names: I. purpurea, Imhoffiella purpurea Nupur et al. 2017, JCM 18851, KCTC 15575, MTCC 12304, Thiorhodococcus sp. AK35, strain AK35
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