STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D779_4080OsmC/Ohr family protein. (138 aa)    
Predicted Functional Partners:
D779_4189
Pyruvate-flavodoxin oxidoreductase.
    
 0.888
D779_4160
Pyruvate-flavodoxin oxidoreductase.
    
 0.884
D779_4132
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
    
 0.801
ffh
Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individu [...]
   
    0.694
D779_4081
Cyclic AMP receptor protein.
       0.555
D779_2246
Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative.
    
  0.480
D779_1497
Soluble pyridine nucleotide transhydrogenase.
    
 0.476
D779_3529
Glutathione reductase.
    
 0.476
metZ
O-acetylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     0.475
mnmE
GTPase and tRNA-U34 5-formylation enzyme TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.453
Your Current Organism:
Imhoffiella purpurea
NCBI taxonomy Id: 1249627
Other names: I. purpurea, Imhoffiella purpurea Nupur et al. 2017, JCM 18851, KCTC 15575, MTCC 12304, Thiorhodococcus sp. AK35, strain AK35
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