STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ54520.1Two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; Sensory domain of two-component sensor kinase. (588 aa)    
Predicted Functional Partners:
APZ54278.1
Two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 0.949
APZ54521.1
Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 
 0.930
APZ54276.1
Signal transduction histidine kinase regulating C4-dicarboxylate transport system.
 
   
  0.900
APZ51565.1
Glutamate synthase (NADPH) large chain.
  
     0.763
APZ51969.1
PAS domain S-box-containing protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box.
 
0.717
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
       0.710
APZ54509.1
Hypothetical protein.
  
 
   0.698
APZ52718.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PAS domain; TIGRFAM: PAS domain S-box.
 
0.620
APZ51204.1
Hypothetical protein.
  
     0.609
APZ51280.1
PFAM: Response regulator receiver domain.
 
 
 0.606
Your Current Organism:
Pelagibaca abyssi
NCBI taxonomy Id: 1250539
Other names: CGMCC 1.12376, LMG 27363, LMG:27363, P. abyssi, Pelagibaca sp. JLT2014, strain JLT2014
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.