STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOW73809.1Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
ribA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
 
 0.999
AOW75353.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
AOW73743.1
Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family.
  
 
 0.941
AOW73769.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.920
AOW73566.1
CoA-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.661
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.620
rpmE2
50S ribosomal protein L31; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to [...]
   
    0.567
AOW75044.1
PTS ascorbate transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.567
AOW73835.1
NAD(FAD)-dependent dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.444
Your Current Organism:
Pediococcus acidilactici
NCBI taxonomy Id: 1254
Other names: BCRC 80335 [[Pediococcus lolii]], CCUG 32235, CIP 103408, DSM 19927 [[Pediococcus lolii]], DSM 20284, JCM 15055 [[Pediococcus lolii]], LMG 11384, LMG:11384, Lactobacillus sp. Lact11, NCFB 2767, NCIMB 12174, P. acidilactici, Pediococcus lindneri, Pediococcus lolii, Pediococcus lolii Doi et al. 2009, strain B213c, strain Back S213C, strain NGRI 0510Q [[Pediococcus lolii]]
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