node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOW73611.1 | AOW74766.1 | A4V11_00720 | A4V11_06945 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.802 |
AOW73611.1 | dnaA | A4V11_00720 | A4V11_06890 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.564 |
AOW73611.1 | topA | A4V11_00720 | A4V11_01855 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.459 |
AOW74285.1 | AOW74766.1 | A4V11_04335 | A4V11_06945 | DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.775 |
AOW74285.1 | dnaA | A4V11_04335 | A4V11_06890 | DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.439 |
AOW74285.1 | topA | A4V11_04335 | A4V11_01855 | DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.459 |
AOW74368.1 | AOW74766.1 | A4V11_04800 | A4V11_06945 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.765 |
AOW74368.1 | dnaG | A4V11_04800 | A4V11_02315 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.489 |
AOW74368.1 | dnaX | A4V11_04800 | A4V11_04825 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.950 |
AOW74368.1 | ssb | A4V11_04800 | A4V11_06925 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.621 |
AOW74368.1 | topA | A4V11_04800 | A4V11_01855 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.505 |
AOW74764.1 | AOW74766.1 | A4V11_06935 | A4V11_06945 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.763 |
AOW74764.1 | rplI | A4V11_06935 | A4V11_06940 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.984 |
AOW74764.1 | ssb | A4V11_06935 | A4V11_06925 | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.462 |
AOW74766.1 | AOW73611.1 | A4V11_06945 | A4V11_00720 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
AOW74766.1 | AOW74285.1 | A4V11_06945 | A4V11_04335 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
AOW74766.1 | AOW74368.1 | A4V11_06945 | A4V11_04800 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.765 |
AOW74766.1 | AOW74764.1 | A4V11_06945 | A4V11_06935 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.763 |
AOW74766.1 | dnaA | A4V11_06945 | A4V11_06890 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.806 |
AOW74766.1 | dnaG | A4V11_06945 | A4V11_02315 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.991 |