STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHM60386.1DnaJ-class molecular chaperone with C-terminal Zn finger domain; COG2214 DnaJ-class molecular chaperone. (320 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.975
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
 
 0.861
AHM58279.1
Amino acid adenylation protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.856
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
 0.836
AHM63100.1
Hypothetical protein.
  
 0.795
AHM60385.1
Hypothetical protein.
       0.791
groL
Chaperonin groel; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 0.724
AHM60428.1
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins.
 
 
 0.644
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
 
 0.610
AHM61674.1
COG0789 Predicted transcriptional regulators.
  
 
 0.610
Your Current Organism:
Flammeovirgaceae bacterium 311
NCBI taxonomy Id: 1257021
Other names: F. bacterium 311
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.