AHM61006.1 protein (Flammeovirgaceae bacterium 311)

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

AHM61006.1

Hypothetical protein. (282 aa)

Predicted Functional Partners:

AHM61007.1

0.951

AHM61003.1

0.900

AHM61008.1

0.895

AHM61005.1

0.845

AHM61001.1

0.840

AHM60814.1

0.649

AHM61002.1

0.602

AHM61004.1

0.566

AHM61049.1

0.565

AHM61582.1

0.527

Your Current Organism:

Flammeovirgaceae bacterium 311

NCBI taxonomy Id: 1257021
Other names: F. bacterium 311

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHM60814.1	AHM61002.1	D770_12800	D770_13740	SMP-30/gluconolaconase/LRE domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.	Hypothetical protein.	0.426
AHM60814.1	AHM61005.1	D770_12800	D770_13755	SMP-30/gluconolaconase/LRE domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.	Hypothetical protein.	0.599
AHM60814.1	AHM61006.1	D770_12800	D770_13760	SMP-30/gluconolaconase/LRE domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.	Hypothetical protein.	0.649
AHM60814.1	AHM61007.1	D770_12800	D770_13765	SMP-30/gluconolaconase/LRE domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.	anti-ECFsigma factor, ChrR.	0.525
AHM61001.1	AHM61002.1	D770_13735	D770_13740	Hypothetical protein.	Hypothetical protein.	0.813
AHM61001.1	AHM61003.1	D770_13735	D770_13745	Hypothetical protein.	anti-ECFsigma factor, ChrR.	0.898
AHM61001.1	AHM61004.1	D770_13735	D770_13750	Hypothetical protein.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.566
AHM61001.1	AHM61005.1	D770_13735	D770_13755	Hypothetical protein.	Hypothetical protein.	0.856
AHM61001.1	AHM61006.1	D770_13735	D770_13760	Hypothetical protein.	Hypothetical protein.	0.840
AHM61001.1	AHM61007.1	D770_13735	D770_13765	Hypothetical protein.	anti-ECFsigma factor, ChrR.	0.858
AHM61001.1	AHM61008.1	D770_13735	D770_13770	Hypothetical protein.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.526
AHM61002.1	AHM60814.1	D770_13740	D770_12800	Hypothetical protein.	SMP-30/gluconolaconase/LRE domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.	0.426
AHM61002.1	AHM61001.1	D770_13740	D770_13735	Hypothetical protein.	Hypothetical protein.	0.813
AHM61002.1	AHM61003.1	D770_13740	D770_13745	Hypothetical protein.	anti-ECFsigma factor, ChrR.	0.911
AHM61002.1	AHM61004.1	D770_13740	D770_13750	Hypothetical protein.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.620
AHM61002.1	AHM61005.1	D770_13740	D770_13755	Hypothetical protein.	Hypothetical protein.	0.574
AHM61002.1	AHM61006.1	D770_13740	D770_13760	Hypothetical protein.	Hypothetical protein.	0.602
AHM61002.1	AHM61007.1	D770_13740	D770_13765	Hypothetical protein.	anti-ECFsigma factor, ChrR.	0.875
AHM61002.1	AHM61008.1	D770_13740	D770_13770	Hypothetical protein.	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.	0.626
AHM61003.1	AHM61001.1	D770_13745	D770_13735	anti-ECFsigma factor, ChrR.	Hypothetical protein.	0.898

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.911

expected number of edges:

10

PPI enrichment p-value:

1.35e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016114

Terpenoid biosynthetic process

8 of 12

2.42

6.7

7.87e-15

GO:0019288

Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

7 of 7

2.6

6.7

4.66e-14

GO:0090407

Organophosphate biosynthetic process

8 of 130

1.39

2.15

9.06e-09

GO:0019637

Organophosphate metabolic process

9 of 177

1.3

2.01

1.62e-09

GO:1901135

Carbohydrate derivative metabolic process

9 of 210

1.23

1.77

6.72e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016725

Oxidoreductase activity, acting on CH or CH2 groups

3 of 8

2.17

1.51

0.0013

GO:0051745

4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity

2 of 2

2.6

1.13

0.0086

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 29

1.61

0.99

0.0086

GO:0046872

Metal ion binding

7 of 488

0.75

0.52

0.0086

GO:0043167

Ion binding

9 of 894

0.6

0.43

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 250

0.9

0.53

0.0261

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4282

Isoprenoid biosynthetic process

7 of 11

2.4

5.82

8.50e-13

CL:4281

Isoprenoid metabolic process, and Carotenoid biosynthesis

8 of 21

2.18

5.54

2.10e-13

CL:4284

Isoprene biosynthesis

5 of 5

2.6

4.56

1.70e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 18

2.24

6.19

1.03e-14

map01110

Biosynthesis of secondary metabolites

9 of 542

0.82

0.78

2.19e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0414

Isoprene biosynthesis

8 of 8

2.6

7.82

1.38e-16

KW-0004

4Fe-4S

3 of 25

1.68

1.22

0.0026

KW-0479

Metal-binding

7 of 228

1.08

1.13

3.48e-05

KW-0560

Oxidoreductase

4 of 118

1.13

0.79

0.0069

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02401

LytB protein

2 of 2

2.6

0.91

0.0220

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