AHM62559.1 protein (Flammeovirgaceae bacterium 311)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

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Score

AHM62559.1

Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator. (190 aa)

Predicted Functional Partners:

paaA

0.893

AHM62556.1

0.794

AHM62555.1

0.714

AHM62557.1

0.562

AHM59538.1

0.500

AHM59968.1

0.445

Your Current Organism:

Flammeovirgaceae bacterium 311

NCBI taxonomy Id: 1257021
Other names: F. bacterium 311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHM59538.1	AHM62556.1	D770_06375	D770_21535	Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.	phenylacetate-CoA oxygenase, paai subunit.	0.507
AHM59538.1	AHM62559.1	D770_06375	D770_21550	Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.	Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator.	0.500
AHM59538.1	paaA	D770_06375	D770_21545	Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.	phenylacetate-CoA oxygenase subunit PaaA.	0.400
AHM59968.1	AHM62556.1	D770_08525	D770_21535	Transketolase central region; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.	phenylacetate-CoA oxygenase, paai subunit.	0.517
AHM59968.1	AHM62559.1	D770_08525	D770_21550	Transketolase central region; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.	Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator.	0.445
AHM59968.1	paaA	D770_08525	D770_21545	Transketolase central region; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.	phenylacetate-CoA oxygenase subunit PaaA.	0.440
AHM62555.1	AHM62556.1	D770_21530	D770_21535	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	phenylacetate-CoA oxygenase, paai subunit.	0.995
AHM62555.1	AHM62557.1	D770_21530	D770_21540	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	0.808
AHM62555.1	AHM62559.1	D770_21530	D770_21550	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator.	0.714
AHM62555.1	paaA	D770_21530	D770_21545	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	phenylacetate-CoA oxygenase subunit PaaA.	0.991
AHM62556.1	AHM59538.1	D770_21535	D770_06375	phenylacetate-CoA oxygenase, paai subunit.	Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.	0.507
AHM62556.1	AHM59968.1	D770_21535	D770_08525	phenylacetate-CoA oxygenase, paai subunit.	Transketolase central region; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.	0.517
AHM62556.1	AHM62555.1	D770_21535	D770_21530	phenylacetate-CoA oxygenase, paai subunit.	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	0.995
AHM62556.1	AHM62557.1	D770_21535	D770_21540	phenylacetate-CoA oxygenase, paai subunit.	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	0.914
AHM62556.1	AHM62559.1	D770_21535	D770_21550	phenylacetate-CoA oxygenase, paai subunit.	Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator.	0.794
AHM62556.1	paaA	D770_21535	D770_21545	phenylacetate-CoA oxygenase, paai subunit.	phenylacetate-CoA oxygenase subunit PaaA.	0.994
AHM62557.1	AHM62555.1	D770_21540	D770_21530	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.	0.808
AHM62557.1	AHM62556.1	D770_21540	D770_21535	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	phenylacetate-CoA oxygenase, paai subunit.	0.914
AHM62557.1	AHM62559.1	D770_21540	D770_21550	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	Transcriptional regulator, tetr family protein; COG1309 Transcriptional regulator.	0.562
AHM62557.1	paaA	D770_21540	D770_21545	Phenylacetic acid degradation b; COG3460 Uncharacterized enzyme of phenylacetate metabolism.	phenylacetate-CoA oxygenase subunit PaaA.	0.872

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.889

expected number of edges:

12

PPI enrichment p-value:

6.09e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006468

Protein phosphorylation

4 of 27

1.49

1.12

0.0029

GO:0036211

Protein modification process

5 of 53

1.29

1.05

0.0018

GO:0016310

Phosphorylation

6 of 90

1.14

0.93

0.0018

GO:0071766

Actinobacterium-type cell wall biogenesis

2 of 3

2.14

0.87

0.0240

GO:0000271

Polysaccharide biosynthetic process

3 of 21

1.47

0.8

0.0203

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004674

Protein serine/threonine kinase activity

4 of 6

2.14

2.27

3.24e-05

GO:0016301

Kinase activity

6 of 76

1.22

1.19

0.00019

GO:0106310

Protein serine kinase activity

2 of 2

2.32

1.05

0.0115

GO:0031177

Phosphopantetheine binding

2 of 3

2.14

1.01

0.0127

GO:0140096

Catalytic activity, acting on a protein

5 of 116

0.95

0.63

0.0115

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:766

Mixed, incl. Protein kinase domain, and Forkhead associated domain

4 of 12

1.84

1.7

0.00027

CL:769

PASTA domain, and Forkhead associated domain

3 of 6

2.02

1.55

0.00091

CL:2820

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

5 of 46

1.36

1.25

0.00050

CL:2858

Polysaccharide biosynthetic process, and Glycosyl transferase, family 1

3 of 18

1.54

1.07

0.0047

CL:2822

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

4 of 36

1.37

1.06

0.0026

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033172

Gas vesicle shell

2 of 2

2.32

0.84

0.0289

GOCC:0034081

Polyketide synthase complex

2 of 3

2.14

0.83

0.0289

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000719

Protein kinase domain

4 of 5

2.22

2.28

3.59e-05

IPR011009

Protein kinase-like domain superfamily

4 of 11

1.88

1.79

0.00019

IPR008271

Serine/threonine-protein kinase, active site

3 of 3

2.32

1.73

0.00055

IPR005543

PASTA domain

3 of 3

2.32

1.73

0.00055

IPR005702

Exopolysaccharide synthesis protein

2 of 2

2.32

0.87

0.0253

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00740

PASTA

3 of 3

2.32

2.03

0.00014

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