STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_317170Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (1039 aa)    
Predicted Functional Partners:
ACA1_215010
Inorganic diphosphatase.
     
 0.944
ACA1_391090
Inorganic diphosphatase; Belongs to the mitochondrial carrier (TC 2.A.29) family.
     
 0.919
ACA1_389290
Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
  
  
 
0.901
ACA1_018760
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
    
 0.572
ACA1_053240
Phosphoglycerate kinase.
   
 
 0.489
ACA1_054360
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
   
  
 0.479
ACA1_367940
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.469
ACA1_203720
E1E2 ATPase subfamily protein.
  
     0.459
ACA1_175060
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
 
 0.456
ACA1_398910
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  
 
 
 0.432
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.