STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_256460Fbox domain containing protein. (654 aa)    
Predicted Functional Partners:
ACA1_058710
Sphase kinase-associated protein, putative; Belongs to the SKP1 family.
    
 0.675
ACA1_382550
Sulfur metabolism negative regulator SconC, putative; Belongs to the SKP1 family.
    
 0.675
ACA1_385430
S-phase kinase-associated protein 1A isoform b, putative; Belongs to the SKP1 family.
    
 0.675
ACA1_290190
SCF ubiquitin ligase complex protein SKP1a, putative; Belongs to the SKP1 family.
    
 0.675
ACA1_288000
NEDD8activating enzyme E1 catalytic subunit.
    
 0.620
ACA1_141950
Cullinassociated and neddylation-dissociated 1, putative.
   
 
  0.612
ACA1_181250
NEDD8-activating enzyme E1 regulatory subunit.
    
 0.523
ACA1_318550
HECTdomain (Ubiquitin-transferase) domain containing protein.
   
  
 0.507
ACA1_368020
RINGbox protein 1, putative.
    
  0.495
ACA1_074760
Signalosome complex protein.
    
  0.439
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.