STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_135680AMP-activated protein kinase, putative. (256 aa)    
Predicted Functional Partners:
ACA1_061610
Rap/ranGAP protein, putative.
   
 0.688
ACA1_093840
Regulatory-associated protein of mTOR, putative.
     
 0.668
ACA1_033670
Rasrelated GTP-binding protein, putative.
    
 0.653
ACA1_039330
Roadblock/LC7 domain containing protein.
   
  0.637
ACA1_377770
WDrepeat protein pop3, putative.
     
 0.636
ACA1_198690
Sestrinlike protein.
     
 0.632
ACA1_172900
Protein phosphatase 2C domain containing protein.
   
  0.628
ACA1_014220
Protein kinase; Belongs to the protein kinase superfamily.
    
 0.626
ACA1_059750
CBLinteracting protein kinase, putative.
    
 0.626
ACA1_183490
Non-specific serine/threonine protein kinase.
    
 0.626
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.