STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_260520Bromodomain containing protein. (871 aa)    
Predicted Functional Partners:
ACA1_232670
BAH domain containing protein.
    
 0.970
ACA1_019960
SWIRM domain containing protein.
   
 0.907
ACA1_020820
TATAbox-binding protein.
    
 0.857
ACA1_265870
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.847
ACA1_261010
Transcription initiation factor IID, 18kD subunit.
    
 0.818
ACA1_209800
Transcription initiation factor tfiid subunit a protein.
    
 0.811
ACA1_389090
Transcription initiation factor iid, 31kd subunit protein.
   
 0.806
ACA1_291010
TAF9 RNA polymerase II, TATA box binding protein (TBP)associated factor, putative.
   
 0.806
ACA1_180590
TRRAP family protein.
    
 0.805
ACA1_180380
FAT domain containing protein; Belongs to the PI3/PI4-kinase family.
    
 0.805
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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