STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_100430IMP2 inner mitochondrial membrane protease family isoform 2, putative. (124 aa)    
Predicted Functional Partners:
ACA1_213570
Signal peptidase complex subunit 3b, putative.
   
 0.856
ACA1_315770
Uncharacterized protein.
    
 0.775
ACA1_275620
Uncharacterized protein.
    
 0.743
ACA1_204030
Uncharacterized protein.
    
 0.663
ACA1_369500
WD domain, Gbeta repeat-containing protein.
    
 0.644
ACA1_370260
TLD family protein.
    
 0.635
ACA1_191590
Uncharacterized protein.
   
 
 0.618
ACA1_175530
Nitrogen permase, putative.
   
 0.596
ACA1_109790
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.573
ACA1_366420
Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
  
 
 0.512
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.