STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_379850Isochorismatase domain containing protein 2, mitochondrial, putative. (225 aa)    
Predicted Functional Partners:
ACA1_283510
Indole3-glycerol phosphate synthase.
  
 
 0.617
ACA1_074670
Arginase; Belongs to the arginase family.
  
 
 0.570
ACA1_174190
Nicotinate phosphoribosyltransferase.
  
 
 0.540
ACA1_171280
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.540
ACA1_219070
Nfrl, putative.
  
 
 0.517
ACA1_385750
Nicotinamide-nucleotide adenylyltransferase/ nicotinate-nucleotide adenylyltransferase, putative.
    
 0.511
ACA1_173790
Nicotinamide-nucleotide adenylyltransferase.
    
 0.511
ACA1_322160
Epoxide hydrolase 2, cytoplasmic, putative.
  
 0.509
ACA1_281460
HAD hydrolase, family IA, variant 3 subfamily protein.
  
 0.509
ACA1_061790
Thiaminephosphate pyrophosphorylase.
 
      0.504
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.