STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_366120SNF2 family Nterminal domain containing protein. (1293 aa)    
Predicted Functional Partners:
ACA1_116890
DNA-directed RNA polymerase II family protein.
    
 0.991
ACA1_158460
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.990
ACA1_300850
CSA protein.
    
 0.989
ACA1_291620
DNAdirected RNA polymerase II subunit rpb4, putative.
    
 0.979
ACA1_190750
DNAdirected RNA polymerase II subunit RPB7, putative.
    
 0.968
ACA1_093730
RNA polymerase subunit.
   
 0.968
ACA1_365330
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.965
ACA1_169330
RNA polymerase Rpb5, Cterminal domain containing protein.
    
  0.965
ACA1_218440
RNA polymerase Rpb3/Rpb11 dimerization domain containing protein.
    
  0.964
ACA1_092940
Uncharacterized protein.
    
  0.963
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.