STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_219040Ubox domain containing protein. (672 aa)    
Predicted Functional Partners:
ACA1_368020
RINGbox protein 1, putative.
    
 0.521
ACA1_300720
WD repeat domain 43 isoform 5, putative.
  
     0.516
ACA1_331480
Membraneassociated ring finger (C3HC4) 2, putative.
  
     0.491
ACA1_091120
Fbox domain containing protein.
  
 
  0.486
ACA1_109770
WD40 repeat-containing protein.
  
 
  0.475
ACA1_342520
Suppressor/Enhancer of Lin12 family member (Sel-10), putative.
  
     0.440
ACA1_373430
WD domain, G-beta repeat-containing protein.
  
     0.420
ACA1_198530
Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
  
     0.416
ACA1_362690
WD domain containing protein.
  
     0.415
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.