STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_214890RHOMBOID-like protein. (434 aa)    
Predicted Functional Partners:
ACA1_074750
5formyltetrahydrofolate cyclo-ligase subfamily protein.
  
    0.490
ACA1_156480
SPFH domain / Band 7 family protein.
   
 0.448
ACA1_209830
Prohibitin.
   
 0.448
ACA1_184250
SPFH domain / Band 7 domain containing protein.
   
 0.448
ACA1_291550
Prohibitin.
   
 0.448
ACA1_389600
Myotubularin related protein 14, putative.
      
 0.412
ACA1_367370
Peptidase, S54 (Rhomboid) subfamily protein.
      
 0.403
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.