STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_164700GMPS family protein. (689 aa)    
Predicted Functional Partners:
ACA1_316550
Inosine5'-monophosphate dehydrogenase.
 
 0.996
ACA1_360160
Adenine phosphoribosyltransferase.
  
 0.979
ACA1_396920
Guanylate kinase.
  
 
 0.975
ACA1_376800
Inosine5'-monophosphate dehydrogenase.
 
 0.968
ACA1_204490
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.958
ACA1_069310
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.937
ACA1_033640
Ser/Thr phosphatase family protein.
     
 0.907
ACA1_062560
Arginine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.906
ACA1_226180
5'nucleotidase.
     
 0.901
ACA1_330420
Ca2+dependent endoplasmic reticulum nucleoside diphosphatase isoform 3, putative.
     
  0.900
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.