STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_203900Phosphatidylethanolamine Nmethyltransferase. (589 aa)    
Predicted Functional Partners:
ACA1_091530
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
  
 0.982
PSD2
Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
     
 0.935
ACA1_295150
Phosphatidylserine decarboxylase.
     
 0.935
ACA1_136520
Uncharacterized protein.
     
 0.929
ACA1_188980
Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.929
ACA1_177710
CDPalcohol phosphatidyltransferase superfamily protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.929
ACA1_222320
CDP-alcohol phosphatidyltransferase superfamily protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.929
ACA1_062510
CDPalcohol phosphatidyltransferase superfamily protein.
     
 0.929
ACA1_054230
CDPalcohol phosphatidyltransferase superfamily protein.
     
 0.929
ACA1_170810
CDPalcohol phosphatidyltransferase superfamily protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.929
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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