STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_163790Oxidoreductase, 2OG-Fe(II) oxygenase family protein. (353 aa)    
Predicted Functional Partners:
ACA1_176860
Glnglu non-discriminatory tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.975
ACA1_132360
Glutamine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.975
ACA1_055430
tRNA (guanine(26)-N(2))-dimethyltransferase.
   
 
 0.546
ACA1_070920
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.512
ACA1_153600
tRNA pseudouridine synthase.
  
 
 0.471
ACA1_258550
NOL1/NOP2/sun domain containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.468
ACA1_361260
Brix domain containing 2, putative.
   
    0.468
ACA1_078030
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
  
  
 0.458
ACA1_066120
Proline-tRNA ligase.
  
 
 0.455
ACA1_400580
Probable ribosome biogenesis protein ACA1_400580; Probable pre-rRNA processing protein involved in ribosome biogenesis.
   
  
 0.450
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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