STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_059540Peptidase D, putative. (485 aa)    
Predicted Functional Partners:
ACA1_219070
Nfrl, putative.
    
 0.653
ACA1_283510
Indole3-glycerol phosphate synthase.
  
  
 0.646
ACA1_390930
Peptidase family M3 protein.
   
 
 0.639
ACA1_296490
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.629
TSFM
Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
   
  
 0.594
ACA1_175450
3-phosphoshikimate 1-carboxyvinyltransferase; Belongs to the EPSP synthase family.
    
  0.589
ACA1_147710
FGGAP repeat domain containing protein.
   
 
 0.551
ACA1_270240
FAD dependent oxidoreductase domain containing protein.
  
 0.511
ACA1_149940
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.511
ACA1_253480
FAD dependent oxidoreductase domain containing protein.
  
 0.511
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.