STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_063460ATPase, AAA domain containing protein. (510 aa)    
Predicted Functional Partners:
ACA1_377980
NPL4 family protein.
   
 0.980
ACA1_330350
SEP domain containing protein.
   
 0.977
ACA1_256540
Histone deacetylase domain containing protein.
   
 0.951
ACA1_372220
Deubiquinating enzyme, putative.
   
 0.875
ACA1_046850
OTU family cysteine protease.
   
 0.875
ACA1_111060
Xtp3transactivated protein, putative.
    
 0.760
ACA1_372050
UBX domain containing protein.
   
 0.742
ACA1_114920
Ubiquitin interaction motif domain containing protein.
   
 0.725
ACA1_264010
Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.
   
 0.703
ACA1_369490
CS domain containing protein.
   
  0.684
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.