STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_0652103-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (387 aa)    
Predicted Functional Partners:
ACA1_068340
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.981
ACA1_101530
6phosphogluconate dehydrogenase NAD-binding domain containing protein.
 
 
 0.948
ACA1_257000
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 
0.905
ACA1_263860
Ribosomal protein s5, nterminal subfamily protein; Belongs to the universal ribosomal protein uS5 family.
    
 
 0.819
ACA1_370280
Ribosomal protein S9, putative; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.816
ACA1_097960
Ribosomal protein L33, putative.
    
 
 0.811
ACA1_143610
Ribosomal protein S17, putative.
    
 
 0.809
ACA1_214330
MRP-S28 domain-containing protein.
   
 
 0.806
ACA1_266930
Hydrolase, NUDIX domain containing protein.
   
 
 0.795
ACA1_191550
Ribosomal protein L13, putative.
  
 
 0.785
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.