STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_208380Longevityassurance protein (LAG1) domain containing protein. (340 aa)    
Predicted Functional Partners:
ACA1_371660
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.948
ACA1_063920
Uncharacterized protein.
    
 0.940
ACA1_176060
Diacylglycerol kinase catalytic domain containing protein.
     
 0.935
ACA1_400540
Sphingosine hydroxylase; Belongs to the sterol desaturase family.
   
 0.934
ACA1_369180
PAP2 superfamily domain containing protein.
    
 0.928
ACA1_068230
Sphingosine kinase, putative.
     
 0.916
ACA1_264580
Sphingomyelin phosphodiesterase, putative.
     
 0.907
ACA1_053480
Longevityassurance protein (LAG1) domain containing protein.
  
  
 
0.904
ACA1_114820
Glucosylceramidase.
     
 0.902
ACA1_190040
Longevityassurance protein (LAG1) domain containing protein.
  
  
 
0.900
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.