STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_369860GTPbinding protein SARA, putative. (146 aa)    
Predicted Functional Partners:
ACA1_020160
Sec16_C domain-containing protein.
   
 0.992
ACA1_289830
WD domain, G-beta repeat-containing protein.
   
 0.991
ACA1_182980
SEC13, putative; Belongs to the WD repeat SEC13 family.
   
 0.965
ACA1_151110
Sec23/Sec24 trunk domain containing protein.
   
 0.919
ACA1_239230
Small copii coat gtpase sar1, putative; Belongs to the small GTPase superfamily. SAR1 family.
  
  
 
0.904
ACA1_070570
Sar1family small GTPase; Belongs to the small GTPase superfamily. SAR1 family.
  
  
 
0.903
ACA1_258690
Vesicle trafficking protein, putative; Belongs to the synaptobrevin family.
   
 0.751
ACA1_347020
Sec23/Sec24 trunk domain containing protein.
    
 0.745
ACA1_298850
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
    
 0.745
ACA1_143940
Type A von Willebrand factor (VWFA) domain containing protein.
    
 0.745
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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