STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_036960Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1309 aa)    
Predicted Functional Partners:
ACA1_092860
WD domain, G-beta repeat-containing protein.
   
 0.995
ACA1_110070
Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.
   
 0.995
ACA1_090230
Chromatin associated protein.
    
 
 0.829
ACA1_341050
CSL zinc finger domain containing protein.
   
 
 0.804
ACA1_182340
NUC153 domain-containing protein.
   
    0.761
ACA1_391500
Angiotonin transactivated protein 1 isoform 2, putative.
    
 0.707
ACA1_055490
ThiF domain containing protein.
   
 
 0.669
ACA1_265930
tRNA(Ile)lysidine synthetase.
   
 
 0.634
ACA1_199040
Pumiliofamily RNA binding repeat domain containing protein.
   
    0.628
ACA1_061540
WD domain, G-beta repeat-containing protein.
   
    0.622
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.