STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_1985002-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (339 aa)    
Predicted Functional Partners:
ACA1_264690
Polyprenyl synthetase superfamily protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.680
ACA1_117250
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.639
ACA1_314220
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
   
 0.617
ACA1_096400
Ubiquinone/menaquinone biosynthesis methyltransferase.
   
 
 0.558
ACA1_281180
Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
   
 
 0.552
ACA1_098390
Methyltransferase, putative.
 
    
 0.472
ACA1_090180
ABC1 domain containing protein.
    
 
 0.468
ACA1_090190
Uncharacterized protein.
    
 
 0.468
ACA1_292830
Cullin 1, putative; Belongs to the cullin family.
 
      0.453
ACA1_342850
FAD-dependent oxidoreductase, putative.
   
 0.437
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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