STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_199620Phosphoinositide 3-kinase family, accessory domain (Pik domain) domain containing protein; Belongs to the PI3/PI4-kinase family. (1188 aa)    
Predicted Functional Partners:
ACA1_267300
Inositol polyphosphate phosphatase, putative.
   
 
 0.913
ACA1_083100
Endonuclease/exonuclease/phosphatase family protein.
   
 
 0.913
ACA1_368260
Phosphoinositide phospholipase C.
     
  0.904
ACA1_214870
Inositol polyphosphate5-phosphatase, 75kDa, putative.
   
 
  0.903
ACA1_318300
C2 calcium/lipidbinding (CaLB) region-containing protein.
    
 0.693
ACA1_156700
Proteintyrosine phosphatase.
    
 0.693
ACA1_223220
Protein-tyrosine-phosphatase.
    
 0.693
ACA1_057530
Phosphatase, putative.
    
 0.693
ACA1_050200
Mammalian PTEN tumor suppressorlike, putative.
    
 0.693
ACA1_252800
Dual specificity phosphatase, catalytic domain containing protein.
    
 0.693
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.