STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_264290Geranylgeranyl diphosphate synthase 1, putative; Belongs to the FPP/GGPP synthase family. (299 aa)    
Predicted Functional Partners:
ACA1_175080
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 0.983
ACA1_182950
Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
    
 0.981
ACA1_340900
Isopentenyldiphosphate delta-isomerase.
  
 
 0.979
ACA1_036930
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.974
ACA1_064640
Farnesyltransferase/geranylgeranyltransferase, putative.
     
 0.953
ACA1_089030
Farnesyldiphosphate farnesyltransferase.
  
 0.952
ACA1_245060
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
   
 0.937
ACA1_108830
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.812
ACA1_391680
Squalene and phytoene synthases superfamily protein.
  
 0.772
ACA1_219750
Geranylgeranyl reductase subfamily protein.
  
 0.759
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.