STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_116500NAD(+)/NADH kinase. (932 aa)    
Predicted Functional Partners:
ACA1_385750
Nicotinamide-nucleotide adenylyltransferase/ nicotinate-nucleotide adenylyltransferase, putative.
  
 
 0.947
ACA1_173790
Nicotinamide-nucleotide adenylyltransferase.
  
 
 0.947
ACA1_088820
Nicotinamide nucleotide transhydrogenase, putative.
   
 0.935
ACA1_174690
NADdependent deacetylase sirtuin, putative.
  
 
 0.920
ACA1_329490
NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.
  
 
 0.916
ACA1_076810
Transcriptional regulator, Sir2, putative.
  
 
 0.916
ACA1_064910
NADdependent deacetylase sirtuin, putative.
  
 
 0.916
ACA1_234290
Sirtuin, putative.
  
 
 0.916
ACA1_117110
Transcriptional regulator, Sir2 family protein.
  
 
 0.916
ACA1_153540
Transcriptional regulator, Sir2 family protein.
  
 
 0.916
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.