STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_116740Omethyltransferase. (415 aa)    
Predicted Functional Partners:
ACA1_232500
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
    
   0.839
ACA1_256390
Histidinol dehydrogenase; Belongs to the HisA/HisF family.
     
 0.547
ACA1_258470
Acetyltransferase, GNAT superfamily protein.
  
  
 0.530
ACA1_360890
GTPbinding protein HflX, putative.
   
  
 0.527
ACA1_175450
3-phosphoshikimate 1-carboxyvinyltransferase; Belongs to the EPSP synthase family.
     
 0.493
ACA1_055650
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
   
  
 0.463
ACA1_144880
Uncharacterized protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
      
 0.457
ACA1_293900
AMP-dependent synthetase and ligase.
      
 0.457
ACA1_142350
Calreticulin.
      
 0.454
ACA1_097000
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
      
 0.440
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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