STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_133510Glutathione peroxidase; Belongs to the glutathione peroxidase family. (361 aa)    
Predicted Functional Partners:
ACA1_089270
Chromatin modificationrelated protein eaf3, putative.
    
 0.801
ACA1_236130
MRG domain-containing protein.
    
 0.801
ACA1_277810
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.796
ACA1_091570
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.697
ACA1_265580
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.697
ACA1_153040
Thioredoxin reductase 1, cytoplasmic, putative.
  
 0.623
ACA1_065240
Glutaredoxin, putative.
  
 
 0.581
ACA1_336860
Glutathione reductase; Maintains high levels of reduced glutathione.
  
 0.580
ACA1_336640
Glutathionedisulfide reductase.
  
 0.580
ACA1_048530
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.576
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.