STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_053220Peptidase family c50 subfamily protein. (1878 aa)    
Predicted Functional Partners:
ACA1_171660
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.967
ACA1_258340
Non-specific protein-tyrosine kinase.
   
 0.953
ACA1_274380
Serine/threonine-protein kinase PLK.
   
 0.953
ACA1_106730
Ser/Thr phosphatase family protein, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.916
ACA1_203910
HEC/Ndc80p family protein.
   
 
 0.912
ACA1_149800
Tetratricopeptide repeat domain containing protein.
    
 0.878
ACA1_068970
Protein kinase.
   
 
 0.878
ACA1_014510
Tetratricopeptide repeat domain containing protein.
    
 0.876
ACA1_155700
Structural maintenance of chromosomes protein.
   
 0.869
ACA1_159980
Anaphase promoting complex subunit 10-like family protein, putative.
    
 0.867
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.