STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_186700ADPribosylation factor subfamily protein. (738 aa)    
Predicted Functional Partners:
ACA1_191590
Uncharacterized protein.
   
 0.845
ACA1_096470
Dual specificity phosphatase, catalytic domain containing protein.
    
 0.807
ACA1_358660
SH3 domain containing protein.
    
 0.713
ACA1_107430
RhoGEF domain containing protein.
    
 0.713
ACA1_112020
RhoGEF domain containing protein.
    
 0.713
ACA1_175570
RhoGEF domain containing protein.
    
 0.713
ACA1_066910
Serine/threonine kinase.
   
 0.666
ACA1_267280
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.619
ACA1_322220
Uncharacterized protein.
   
 0.595
ACA1_071300
SH3 domain containing protein.
   
 0.595
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.