STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_206010Proliferating cell nuclear antigen, cterminal domain containing protein. (231 aa)    
Predicted Functional Partners:
ACA1_376610
DEAD/DEAH box helicase domain containing protein.
    
 0.995
ACA1_252580
Replication factor C protein.
  
 0.982
ACA1_040860
DNA replication factor C complex subunit 2, putative.
  
 0.962
ACA1_289040
DNA polymerase.
  
 0.953
ACA1_289820
DNA polymerase epsilon subunit B protein.
   
 0.952
ACA1_202440
ImpB/MucB/SamB family protein.
   
 0.948
ACA1_054730
DNA polymerase kappa, putative.
   
 0.930
ACA1_369120
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
  
  0.929
ACA1_369010
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
  
 0.928
ACA1_062530
DNA polymerase.
  
 0.924
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.