STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_055000I/LWEQ domain containing protein. (649 aa)    
Predicted Functional Partners:
ACA1_096470
Dual specificity phosphatase, catalytic domain containing protein.
   
 0.993
ACA1_363740
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.924
ACA1_261040
Uncharacterized protein.
    
 0.836
ACA1_167070
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.836
ACA1_171680
PX domain containing protein.
    
 0.682
ACA1_321190
Adaptin earbinding coat-associated protein 2 (NECAP-2) isoform 2, putative.
     
 0.614
ACA1_065770
Phosphatidylinositol 3kinase; Belongs to the PI3/PI4-kinase family.
   
 
  0.612
ACA1_138990
AP-1 complex subunit gamma.
    
 0.585
ACA1_175550
Adaptin subfamily protein.
    
 0.585
ACA1_064250
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
    
 0.564
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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