STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_055650Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (415 aa)    
Predicted Functional Partners:
ACA1_055660
Lipoyl(Octanoyl) transferase.
 
 0.998
ACA1_116630
Lipoyltransferase and lipoateprotein ligase.
 
 
 0.997
ACA1_173270
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 0.923
ACA1_149490
Biotin/lipoate A/B protein ligase domain containing protein.
  
 
 0.826
ACA1_315760
Ribosomal protein L13, putative.
 
    0.782
ACA1_340900
Isopentenyldiphosphate delta-isomerase.
 
    0.605
ACA1_036260
Flavocytochrome c subfamily protein.
  
  
 0.584
ACA1_264380
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 
      0.554
ACA1_333350
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
     
 0.550
ACA1_119180
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
      0.546
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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