STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_053910Dihydroxy-acid dehydratase. (672 aa)    
Predicted Functional Partners:
ACA1_130190
HMGL family domain containing protein.
  
 
 0.971
ACA1_369090
2hydroxyacyl-CoA lyase 1, putative; Belongs to the TPP enzyme family.
 
  
 0.922
ACA1_202700
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.920
ACA1_064920
Branchedchain amino acid aminotransferase.
  
 0.920
ACA1_208240
Aminotransferase, class IV superfamily protein.
  
 0.920
ACA1_154220
Pyridoxalphosphate dependent superfamily protein.
 
  
 0.919
ACA1_309320
Glucose-6-phosphate 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.
 
  
 0.909
ACA1_256390
Histidinol dehydrogenase; Belongs to the HisA/HisF family.
  
  
 0.901
ACA1_103160
Serine/threonine dehydratase.
  
  
 0.853
ACA1_155580
Chitin synthase.
   
 0.850
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.